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2 changed files with 786 additions and 281 deletions
24
report.Rmd
24
report.Rmd
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@ -546,23 +546,20 @@ recode.age <- function(dat, ages) {
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dat.age.rec <- dat[!is.na(dat$age.rec), ]
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class.age <- function(age) {
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if (age < 2) {
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return("0,1")
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return("0-1")
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} else if (age < 6) {
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return("2,3,4,5")
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return("2-5")
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} else if (age < 11) {
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return("6,7,8,9,10")
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return("6-10")
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} else if (age < 19) {
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return("11-18")
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}
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}
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```
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```{r}
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dat.age.rec$age.group <- sapply(dat.age.rec$age.rec, class.age) |>
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factor(levels = c(
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"0,1",
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"2,3,4,5",
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"6,7,8,9,10",
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"0-1",
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"2-5",
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"6-10",
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"11-18"
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))
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@ -574,9 +571,6 @@ cox.age.rec <- coxph(Surv(follow.up, death) ~ age.group, data = dat.age.rec)
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emmeans(cox.age.rec, pairwise ~ age.group, type = "response")
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```
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```{r}
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cox.age.rec |> ggsurvfit()
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```
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# Exercise 7
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@ -705,6 +699,7 @@ H1: PH-assumption doesn't hold
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# different cox model!!
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cox.final <- coxph(Surv(follow.up, death) ~ tx.type + age.rec + hla.match + age.donor, data = dat)
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cox.zph(cox.final)
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cox.final
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```
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@ -715,6 +710,11 @@ A non-random pattern or slope in a plot of scaled residuals against time indicat
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plot(cox.zph(cox.final))
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```
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```{r, fig.width=10, fig.height=10}
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plot(cox.zph(cox.final))
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```
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NOTES:
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